This study assessed the attitudes and patterns of self medication among undergraduate students in Niger Delta University. 200 students from five faculties of the institution were selected for the study. Data collected were analyzed using SPSS version 16. Majority were aged between 15-25 years; 42.5% were males; 90% were single; 67.5% lived on-campus. Self-medication prevalence was 68.5%; perception of nature of ailment as being mild (37.5%) was a major reason given for self-medication; analgesics were predominantly involved. Self-decision (47.5%) was implicated as major determinant for self-medication. There is need to reinforce responsible self-medication among this population. Download