Microfinance institutions (MFIs) are regarded as powerful avenues for poverty alleviation globally and help to achieving the United Nations' Sustainable Development Goals (SDGs). The objective of the paper therefore examined potential challenges affecting microfinance institutions as a vehicle for achieving sustainability. Cross-sectional survey design approach was used for data collection through questionnaires. Forty (40) MFIs across Ghana and 400 of such staff were interviewed in the survey. Descriptive statistics and standard multiple regressions were employed for data analysis.
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